Comparing the effectiveness of medications for opioid use disorder
MOUD Comparative Effectiveness Study
This study is looking at how well different medications, like buprenorphine-naloxone and extended-release naltrexone, help people who are recovering from opioid use disorder stay on track and avoid overdoses, especially for those who have recently gone through detox.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston Medical Center NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-11082219 on NIH RePORTER |
What this research studies
This research investigates the effectiveness of different medications used to treat opioid use disorder, specifically focusing on buprenorphine-naloxone and extended-release naltrexone. By utilizing a comprehensive database that links various state-level datasets, the study aims to analyze real-world outcomes related to medication retention and opioid overdose rates. Patients who have undergone opioid detoxification will be a key focus, as they are at high risk for relapse. The research seeks to provide insights that could improve treatment strategies and patient outcomes in the community.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have recently undergone opioid detoxification and are seeking treatment for opioid use disorder.
Not a fit: Patients who are not seeking treatment for opioid use disorder or who have not undergone detoxification may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment options and better retention rates for patients with opioid use disorder.
How similar studies have performed: Previous research has shown promising results in comparing the effectiveness of different medications for opioid use disorder, indicating that this approach has potential for meaningful insights.
Where this research is happening
Boston, United States
- Boston Medical Center — Boston, United States (Active)
Researchers
- Principal investigator: Larochelle, Marc — Boston Medical Center
- Study coordinator: Larochelle, Marc
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.