Comparing the effectiveness and safety of different flu vaccines for dialysis patients
Official title: Comparative Effectiveness and Safety of Adjuvanted and Other Influenza Vaccine Technologies Among Patients Receiving Dialysis
Funded at Washington University · NIH-10888410 · Data updated 2026-11-12
This study is looking at how well different flu vaccines work for people on dialysis, especially new types that might be better than the usual ones, to help find the safest and most effective options for keeping you healthy during flu season.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project start | July 14, 2023 |
| Project end | June 30, 2026 |
| Funding year | 2024 |
| Award (this year) | $234,167 |
| NIH project number | 5R21AI178408-02 |
| Project ID | NIH-10888410 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults aged 21 and older who are currently receiving dialysis treatment.
✕Less likely to help
Patients who are not undergoing dialysis or those who are not eligible for influenza vaccination may not benefit from this research.
What this research studies
This research investigates how well different types of influenza vaccines work for patients undergoing dialysis, particularly focusing on newly licensed adjuvanted and recombinant vaccines. The study aims to compare these vaccines' effectiveness and safety against standard-dose vaccines, which have shown limited effectiveness in this population. By analyzing immune responses and potential adverse effects, the research seeks to provide clearer guidance on the best vaccination strategies for dialysis patients. Participants will be monitored for their immune response and any side effects following vaccination.
Why it matters
Potential benefit: If successful, this research could lead to improved vaccination strategies that significantly reduce influenza-related hospitalizations and mortality among dialysis patients.
How similar studies have gone: While there is evidence suggesting the effectiveness of adjuvanted and recombinant vaccines in the general population, this specific comparison in dialysis patients is novel and has not been extensively studied.
Where this research is happening
-
Washington University
Saint Louis, United States Active
Researchers
- Principal investigator: Butler, Anne Mobley — Washington University
- Study coordinator: Butler, Anne Mobley
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.