Comparing surgical and medical treatments for type 2 diabetes in children

Surgical or Medical Treatment for Pediatric Type 2 Diabetes (ST2OMP)

NIH-funded research Cincinnati Childrens Hosp Med Ctr · NIH-10694998

This study is looking at how well a weight-loss surgery called vertical sleeve gastrectomy works compared to advanced medical treatments for helping teenagers with type 2 diabetes manage their blood sugar and health.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionCincinnati Childrens Hosp Med Ctr NIH-funded
Lab location1 site (Cincinnati, United States)
Project IDNIH-10694998 on NIH RePORTER

What this research studies

This research investigates the effectiveness of vertical sleeve gastrectomy (VSG) compared to advanced medical therapy (AMT) in treating youth-onset type 2 diabetes (T2D). The study aims to enroll 90 adolescents with T2D and assess how these two treatment approaches impact blood sugar control and related health issues. By exploring the underlying mechanisms of these treatments, the research seeks to provide insights into better management strategies for young patients suffering from T2D. The research is conducted at two sites with specialized pediatric medical and surgical expertise.

Who could benefit from this research

Good fit: Ideal candidates for this research are adolescents diagnosed with type 2 diabetes who are struggling to manage their condition with current medical therapies.

Not a fit: Patients who are not adolescents or those with type 1 diabetes may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatment options for adolescents with type 2 diabetes, potentially reducing their reliance on insulin and decreasing associated health complications.

How similar studies have performed: Previous studies have shown promising results for metabolic bariatric surgery in adults with type 2 diabetes, but this specific approach in adolescents is still being explored.

Where this research is happening

Cincinnati, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.