Comparing surgery and non-surgical options for knee pain from meniscal tears

Surgery vs. conservative care for meniscal tear after unsuccessful PT: an RCT

NIH-funded research Brigham and Women's Hospital · NIH-10798241

This study is looking at how well surgery and non-surgical treatments work for older adults with knee pain from meniscal tears who haven't found relief from physical therapy, and if you're still in pain after trying therapy, you can join to see if surgery or a special non-surgical plan helps you feel better over the next two years.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionBrigham and Women's Hospital NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-10798241 on NIH RePORTER

What this research studies

This research investigates the effectiveness of surgical versus non-surgical treatments for knee pain caused by meniscal tears in older adults who have not found relief from physical therapy. Participants will first undergo a standardized physical therapy regimen, and those who continue to experience pain will be invited to join a randomized controlled trial. They will have the option to receive either arthroscopic surgery or a comprehensive non-surgical treatment plan that includes injections and enhanced physical therapy. The study aims to assess pain relief and overall outcomes over a two-year period.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals aged 45 and older who have knee pain and meniscal tears and have not responded to physical therapy.

Not a fit: Patients who have not undergone physical therapy or those with other knee conditions unrelated to meniscal tears may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide clearer guidance on the best treatment options for older adults suffering from knee pain due to meniscal tears.

How similar studies have performed: Previous research has shown that physical therapy can be as effective as surgery for knee pain, but this specific comparison of treatments after unsuccessful PT is novel.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.