Comparing standard and high doses of buprenorphine for treating opioid addiction

STANDARD AND HIGH DOSE ED BUPRENORPHINE INDUCTION. 09/15/2023 - 05/31/2026. N01DA-22-2253. TASK ORDER 75N95023F00005 (TO9).

NIH-funded research The Emmes Company, LLC · NIH-10938754

This study is looking at whether taking a regular or a higher dose of buprenorphine can better help people struggling with opioid addiction to reduce their use and support their recovery.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionThe Emmes Company, LLC NIH-funded
Lab location1 site (Rockville, United States)
Project IDNIH-10938754 on NIH RePORTER

What this research studies

This research investigates the effectiveness of standard versus high doses of buprenorphine in helping individuals overcome opioid addiction. Participants will receive either dosage to determine which is more effective in reducing opioid misuse and supporting recovery. The study is part of a larger initiative aimed at finding rapid and sustainable solutions to the opioid crisis, focusing on improving treatment strategies for those affected by opioid dependence.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who are dependent on opioids and seeking treatment.

Not a fit: Patients who are not dependent on opioids or those who are not seeking treatment may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective treatment options for individuals struggling with opioid addiction.

How similar studies have performed: Previous research has shown promising results in using buprenorphine for opioid addiction treatment, indicating that this approach has potential for success.

Where this research is happening

Rockville, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.