Comparing risk factors for men with and without prostate cancer
A Comparative Study of Risk Factors for Men with and without Prostate Cancer at the VA Medical Center in Durham
This study is looking at how certain treatments for prostate cancer, like hormone therapy, affect men's health and whether a special diet can help improve their well-being during treatment.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cedars-Sinai Medical Center NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project ID | NIH-11064573 on NIH RePORTER |
What this research studies
This research investigates the differences in risk factors between men diagnosed with prostate cancer and those without it, focusing on the effects of androgen deprivation therapy (ADT) and its associated metabolic changes. The study utilizes a fasting-mimicking diet (FMD) to assess its impact on insulin, glucose, and other biological markers in prostate cancer patients. By analyzing these factors, the research aims to identify potential strategies to mitigate treatment-related toxicities and improve overall health outcomes for men undergoing prostate cancer treatment.
Who could benefit from this research
Good fit: Ideal candidates for this research include men diagnosed with prostate cancer, particularly those undergoing androgen deprivation therapy.
Not a fit: Patients with prostate cancer who are not undergoing treatment or those with other unrelated health conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved management of prostate cancer treatment side effects and better health outcomes for patients.
How similar studies have performed: Previous studies have shown promising results with fasting-mimicking diets in improving metabolic health and delaying tumor progression in animal models, suggesting potential for success in human applications.
Where this research is happening
Los Angeles, United States
- Cedars-Sinai Medical Center — Los Angeles, United States (Active)
Researchers
- Principal investigator: Freedland, Stephen Jay — Cedars-Sinai Medical Center
- Study coordinator: Freedland, Stephen Jay
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.