Comparing new radiation therapies for cancer treatment
Core C: Comparative Pathology Core
This study is looking at new types of radiation therapy, called Proton and Carbon Particle FLASH Radiotherapy, to see if they can better protect healthy tissues while still fighting cancer, and it's being tested in animal models to understand how these treatments work.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-11030338 on NIH RePORTER |
What this research studies
This research investigates how Proton and Carbon Particle FLASH Radiotherapy can better protect normal tissues while effectively controlling cancer growth compared to standard particle radiotherapy. It utilizes preclinical animal models to assess the biological effects of these therapies through detailed histopathological evaluations. The Comparative Pathology Core at the University of Pennsylvania plays a crucial role in ensuring accurate collection and analysis of tissue samples, which helps in understanding the impact of these new radiation techniques on both cancerous and normal tissues.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients with cancer who may benefit from advanced radiation therapies.
Not a fit: Patients who are not undergoing radiation therapy or those with non-cancerous conditions may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved cancer treatment options that minimize damage to healthy tissues.
How similar studies have performed: Previous research has shown promising results with advanced radiation therapies, indicating potential for significant improvements in treatment outcomes.
Where this research is happening
Philadelphia, United States
- University of Pennsylvania — Philadelphia, United States (Active)
Researchers
- Principal investigator: Radaelli, Enrico — University of Pennsylvania
- Study coordinator: Radaelli, Enrico
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.