Comparing medications for treating first episode psychosis
Comparative effectiveness of pharmacologic strategies to treat first episode psychosis
['FUNDING_OTHER'] · MCLEAN HOSPITAL · NIH-10918301
This study is looking at how well different antipsychotic medications work for people who are having their first experience with psychosis, with the goal of helping them stick to their treatment so they can avoid going back to the hospital.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | MCLEAN HOSPITAL (nih funded) |
| Locations | 1 site (BELMONT, UNITED STATES) |
| Trial ID | NIH-10918301 on ClinicalTrials.gov |
What this research studies
This research investigates the effectiveness of different antipsychotic medications for individuals experiencing their first episode of psychosis. It aims to enhance adherence to these medications, which are crucial for reducing the risk of relapse and hospitalization. The study will utilize observational data to emulate findings from previous randomized trials, allowing for a more comprehensive understanding of treatment effectiveness across diverse patient populations. By benchmarking against established trials, the research seeks to provide insights that can improve clinical practices in managing first episode psychosis.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals aged 12 to 21 who are experiencing their first episode of psychosis and are being treated with antipsychotic medications.
Not a fit: Patients who are not experiencing their first episode of psychosis or those who are not prescribed antipsychotic medications may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies that enhance medication adherence and reduce relapse rates in patients with first episode psychosis.
How similar studies have performed: Previous research has shown success in using observational data to complement findings from randomized trials, making this approach both relevant and promising.
Where this research is happening
BELMONT, UNITED STATES
- MCLEAN HOSPITAL — BELMONT, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: HERNAN, MIGUEL — MCLEAN HOSPITAL
- Study coordinator: HERNAN, MIGUEL
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.