Comparing long-acting treatments for opioid use disorder in incarcerated adults

Long-acting buprenorphine vs. naltrexone opioid treatments in CJS-involved adults

['FUNDING_U01'] · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · NIH-11044583

This study is looking at how well two long-lasting medications, buprenorphine and naltrexone, can help adults with opioid addiction who are in jail and getting ready to go back into the community, to see if they can support their recovery after release.

Quick facts

Phase['FUNDING_U01']
Study typeNih_funding
SexAll
SponsorNEW YORK UNIVERSITY SCHOOL OF MEDICINE (nih funded)
Locations1 site (NEW YORK, UNITED STATES)
Trial IDNIH-11044583 on ClinicalTrials.gov

What this research studies

This research evaluates the effectiveness of two long-acting medications, buprenorphine and naltrexone, for treating opioid use disorder in adults who are currently incarcerated and preparing for release. The study involves multiple sites and aims to gather high-quality data on how these treatments perform in a criminal justice setting. Participants will be recruited from various correctional facilities, and the research will assess how well these medications help manage opioid addiction and support recovery post-release.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults with moderate-to-severe opioid use disorders who are currently incarcerated and have an upcoming release date.

Not a fit: Patients who are not currently incarcerated or those with mild opioid use disorders may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could improve treatment options for opioid use disorder in incarcerated individuals, potentially leading to better recovery outcomes after release.

How similar studies have performed: Previous research has shown promise in using long-acting medications for opioid use disorder, but this specific approach in a criminal justice setting is relatively novel.

Where this research is happening

NEW YORK, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.