Comparing kidney function estimates using cystatin C and creatinine in older adults
The Clinical Applications of the Difference in Estimated Glomerular Filtration Rate by Cystatin C vs. Creatinine (eGFRDiff)
['FUNDING_OTHER'] · UNIVERSITY OF CALIFORNIA, SAN DIEGO · NIH-11080759
This study is looking at how two different tests for kidney function—one using cystatin C and the other using creatinine—compare in older adults, with the goal of helping doctors better understand kidney health and adjust medications for elderly patients.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA, SAN DIEGO (nih funded) |
| Locations | 1 site (LA JOLLA, UNITED STATES) |
| Trial ID | NIH-11080759 on ClinicalTrials.gov |
What this research studies
This research investigates how the estimated glomerular filtration rate (eGFR) calculated from cystatin C compares to that calculated from creatinine in older adults. By analyzing these differences, the study aims to improve prognosis and optimize drug dosing for elderly patients with kidney issues. The research will involve advanced statistical methods and a multidisciplinary team to ensure comprehensive evaluation and accurate results. Patients may be monitored over time to assess the long-term implications of these findings.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals aged 65 and older who may have kidney function concerns.
Not a fit: Patients under the age of 65 or those without kidney function issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate kidney function assessments and better medication management for older adults.
How similar studies have performed: Previous research has shown promising results in using cystatin C for kidney function assessment, indicating potential for success in this approach.
Where this research is happening
LA JOLLA, UNITED STATES
- UNIVERSITY OF CALIFORNIA, SAN DIEGO — LA JOLLA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: POTOK, OLIVIA ALISON — UNIVERSITY OF CALIFORNIA, SAN DIEGO
- Study coordinator: POTOK, OLIVIA ALISON
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.