Comparing frozen embryo transfer methods to improve pregnancy outcomes
2/3 A randomized controlled trial of frozen embryo transfers performed in modified natural versus programmed cycles (NatPro)
['FUNDING_R01'] · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · NIH-10684173
This study is looking at how two different ways of transferring frozen embryos might affect pregnancy health, especially the risk of high blood pressure issues like preeclampsia, and it's for people who are using assisted reproductive technology to help them get pregnant.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR (nih funded) |
| Locations | 1 site (OKLAHOMA CITY, UNITED STATES) |
| Trial ID | NIH-10684173 on ClinicalTrials.gov |
What this research studies
This research investigates the effects of two different methods of frozen embryo transfer (FET) on pregnancy outcomes, specifically focusing on the risk of hypertensive disorders like preeclampsia. Patients undergoing assisted reproductive technology will be randomly assigned to either a modified natural cycle or a programmed cycle for their embryo transfer. The study aims to determine which method leads to better health outcomes for both mothers and infants by analyzing cardiovascular responses and live birth rates. By participating, patients may contribute to important findings that could influence future fertility treatments.
Who could benefit from this research
Good fit: Ideal candidates for this research are women undergoing frozen embryo transfer as part of assisted reproductive technology.
Not a fit: Patients who are not undergoing frozen embryo transfer or those with contraindications to pregnancy may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to safer embryo transfer protocols that reduce the risk of complications during pregnancy.
How similar studies have performed: Previous studies have indicated that different protocols for frozen embryo transfer can significantly impact pregnancy outcomes, suggesting that this research could build on established findings.
Where this research is happening
OKLAHOMA CITY, UNITED STATES
- UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR — OKLAHOMA CITY, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: HANSEN, KARL RICHARD — UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR
- Study coordinator: HANSEN, KARL RICHARD
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.