Comparing flexible and standard aerobic exercise for breast cancer patients

Flexible versus Standard Aerobic Training Dosing in Primary Breast Cancer: A Randomized and Response-Adapted Trial

NIH-funded research Sloan-Kettering Inst Can Research · NIH-10916471

This study is looking at how different ways of doing aerobic exercise can help improve fitness for women being treated for breast cancer, comparing a flexible workout plan that adjusts to how each person feels with a standard plan, to see which one works better during and after chemotherapy.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionSloan-Kettering Inst Can Research NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-10916471 on NIH RePORTER

What this research studies

This research investigates how different approaches to aerobic exercise can affect cardiorespiratory fitness in patients undergoing treatment for primary breast cancer. It compares a flexible exercise dosing method, where the intensity and duration of workouts are adjusted based on individual tolerance, to a standard fixed dosing approach. The study aims to determine which method is more effective in improving fitness levels during and after chemotherapy. By tailoring exercise regimens to each patient's needs, the research seeks to enhance adherence and overall health outcomes.

Who could benefit from this research

Good fit: Ideal candidates for this research are inactive adults diagnosed with primary breast cancer who are undergoing chemotherapy.

Not a fit: Patients who are already highly active or those with advanced cancer stages may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved fitness and reduced health risks for breast cancer patients undergoing chemotherapy.

How similar studies have performed: While aerobic training has been shown to be beneficial during chemotherapy, this specific flexible dosing approach has not been previously tested in cancer settings.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Breast CancerBreast Cancer Patient
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.