Comparing embolization and surgery for treating chronic subdural hematomas
Chronic Subdural Hematoma Treatment with Embolization vs Surgery or MedicalManagement Study (CHESS)
['FUNDING_OTHER'] · UNIVERSITY OF TEXAS MED BR GALVESTON · NIH-11142185
This study is looking at whether a new treatment called middle meningeal artery embolization (MMAE) is better than traditional surgery for helping people with chronic subdural hematomas, and it’s for patients who have moderate symptoms and want to see if this new option can lead to fewer surgeries and better recovery in the next six months.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF TEXAS MED BR GALVESTON (nih funded) |
| Locations | 1 site (GALVESTON, UNITED STATES) |
| Trial ID | NIH-11142185 on ClinicalTrials.gov |
What this research studies
This research investigates the effectiveness of middle meningeal artery embolization (MMAE) compared to conventional surgery for treating chronic subdural hematomas (CSDH). It aims to determine if MMAE can reduce the need for additional surgeries and improve patient outcomes within 180 days. The study will involve multiple centers and will randomly assign patients with moderately symptomatic CSDH to receive either MMAE or conventional surgery. Patients will be monitored for safety and efficacy, focusing on neurological status and adverse events.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with moderately symptomatic chronic subdural hematomas who are considering treatment options.
Not a fit: Patients with severe symptoms or those who have already undergone treatment for chronic subdural hematomas may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a less invasive treatment option for patients with chronic subdural hematomas, potentially leading to better outcomes and fewer complications.
How similar studies have performed: Preliminary experiences suggest that MMAE may be more effective than conventional surgery, but this research is among the first to rigorously compare these approaches in a randomized controlled trial.
Where this research is happening
GALVESTON, UNITED STATES
- UNIVERSITY OF TEXAS MED BR GALVESTON — GALVESTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: KAN, PETER TZE MAN — UNIVERSITY OF TEXAS MED BR GALVESTON
- Study coordinator: KAN, PETER TZE MAN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.