Comparing electronic cigarettes and nicotine replacement therapy for obese smokers

A Comparison of Electronic Cigarettes and Combination Nicotine Replacement Therapy among Individuals with Obesity who Smoke

NIH-funded research Brown University · NIH-10849987

This study is looking at how electronic cigarettes and nicotine replacement therapy can help people who smoke and are also dealing with obesity to quit smoking while keeping their weight in check.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionBrown University NIH-funded
Lab location1 site (Providence, United States)
Project IDNIH-10849987 on NIH RePORTER

What this research studies

This research investigates how electronic cigarettes (EC) and combination nicotine replacement therapy (NRT) can help individuals who smoke and are also obese. It focuses on understanding the unique challenges faced by this group, such as increased risk of health issues and concerns about weight gain when quitting smoking. The study aims to determine which method is more effective in helping these individuals quit smoking while managing their weight. Participants will be monitored for adherence and health outcomes over the course of the research.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who smoke cigarettes and have obesity, particularly those who are concerned about weight gain when attempting to quit.

Not a fit: Patients who do not smoke or who are not classified as obese may not receive any benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide a more effective smoking cessation method tailored for individuals with obesity, potentially improving their overall health and reducing smoking-related diseases.

How similar studies have performed: Previous research has shown promise in using electronic cigarettes as a smoking cessation tool, particularly for populations with unique challenges, suggesting that this approach may be effective.

Where this research is happening

Providence, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.