Comparing EEG-guided treatments for seizures in patients with acute brain injuries

Comparative Effectiveness of EEG-Guided Anti-Seizure Treatment in Acute Brain Injury

['FUNDING_R01'] · MASSACHUSETTS GENERAL HOSPITAL · NIH-10993209

This study is looking at how well EEG-guided treatments can help reduce seizures in people who have had serious brain injuries, like strokes or trauma, to improve their recovery and overall health.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorMASSACHUSETTS GENERAL HOSPITAL (nih funded)
Locations1 site (BOSTON, UNITED STATES)
Trial IDNIH-10993209 on ClinicalTrials.gov

What this research studies

This research investigates the effectiveness of EEG-guided anti-seizure treatments for patients suffering from acute brain injuries, such as strokes or trauma. It aims to understand how these treatments can reduce seizure activity, which is common in this patient population and can lead to increased risks of death and disability. By utilizing a large multi-center EEG registry, the study will analyze EEG data to better inform treatment decisions and improve patient outcomes. The research addresses the challenges of balancing the adverse effects of seizures with the side effects of anti-seizure medications.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who have experienced an acute brain injury and are at risk for seizures.

Not a fit: Patients who do not have acute brain injuries or are not at risk for seizures may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective and safer treatment options for patients with acute brain injuries at risk of seizures.

How similar studies have performed: Previous research has shown promise in using EEG data to guide treatment decisions in similar patient populations, indicating that this approach may be effective.

Where this research is happening

BOSTON, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Acquired brain injury

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.