Comparing early and delayed umbilical cord clamping in newborns with congenital heart disease
1/2 CORD-CHD: Clamp OR Delay among neonates with Congenital Heart Disease
This study is looking at how two different ways of clamping the umbilical cord—either right after birth or a little later—affect newborns with congenital heart disease, to see which method helps these babies the most.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Research Inst Nationwide Children's Hosp NIH-funded |
| Lab location | 1 site (Columbus, United States) |
| Project ID | NIH-11062509 on NIH RePORTER |
What this research studies
This research investigates the effects of two different umbilical cord clamping methods—early clamping and delayed clamping—on newborns diagnosed with congenital heart disease. The study aims to determine which method is more beneficial for these high-risk infants, as previous research has shown advantages of delayed clamping in healthy newborns. By conducting a randomized controlled trial, the researchers will assess outcomes such as blood transfer from the placenta and potential impacts on iron levels and neurodevelopment. This trial is particularly important because the unique physiological characteristics of infants with congenital heart disease may influence the effectiveness of these clamping methods.
Who could benefit from this research
Good fit: Ideal candidates for this research are newborns diagnosed with congenital heart disease who are undergoing delivery.
Not a fit: Patients who are not newborns or those without congenital heart disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved health outcomes for newborns with congenital heart disease by identifying the optimal cord clamping method.
How similar studies have performed: Previous studies have shown success with delayed cord clamping in healthy newborns, but this research is novel as it focuses specifically on infants with congenital heart disease.
Where this research is happening
Columbus, United States
- Research Inst Nationwide Children's Hosp — Columbus, United States (Active)
Researchers
- Principal investigator: Backes, Carl — Research Inst Nationwide Children's Hosp
- Study coordinator: Backes, Carl
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.