Comparing diets to lower blood sugar in polycystic ovary syndrome
Glycemic reduction approaches in polycystic ovary syndrome: a comparative effectiveness study
This compares different diet plans to help women with PCOS lower blood sugar, lose weight, and improve insulin-related hormone levels.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project ID | NIH-11238894 on NIH RePORTER |
What this research studies
You would be invited to follow one of several nutrition plans—such as a standard diet, a DASH-style plan, or a very low-carbohydrate plan—for a set period while researchers track your health. The team will collect blood tests, body weight and BMI measures, and hormone or insulin-related markers, and ask about diet adherence and symptoms like acne. Visits will include counseling and follow-up to support the assigned eating plan and monitor changes. The researchers will compare how each approach affects glucose control, weight, and PCOS-related hormonal measures over time.
Who could benefit from this research
Good fit: Women aged 21 or older with a diagnosis of PCOS, especially those who are overweight or obese and concerned about blood sugar or insulin resistance, are ideal candidates.
Not a fit: People without PCOS, men, pregnant women, or anyone unable to follow dietary changes are unlikely to benefit directly from this work.
Why it matters
Potential benefit: If successful, this could identify which diet best reduces diabetes risk and improves weight and hormonal symptoms for women with PCOS.
How similar studies have performed: Prior trials show modest metabolic benefits from lower-carbohydrate diets in PCOS and stronger effects of very low-carb diets in type 2 diabetes, but very low-carb approaches have not been well tested specifically in PCOS.
Where this research is happening
Ann Arbor, United States
- University of Michigan at Ann Arbor — Ann Arbor, United States (Active)
Researchers
- Principal investigator: Saslow, Laura — University of Michigan at Ann Arbor
- Study coordinator: Saslow, Laura
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.