Comparing cardiovascular treatment outcomes across wealthy countries

Comparing approval, adoption/de-adoption and outcomes for advanced cardiovascular procedures across high-income countries

NIH-funded research Harvard Medical School · NIH-11041134

This study looks at how new heart treatments are approved and used in wealthy countries, aiming to find out why patients in the US often have worse heart health outcomes despite spending more on healthcare, so that we can improve treatment and policies for everyone.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionHarvard Medical School NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-11041134 on NIH RePORTER

What this research studies

This research investigates how advanced cardiovascular procedures are approved and adopted in high-income countries, focusing on the differences in outcomes for patients. By analyzing health technology assessments (HTA) and their impact on the use of new treatments, the study aims to understand why the US has poorer cardiovascular outcomes despite higher healthcare spending. Patients may benefit from insights that could lead to improved treatment protocols and better healthcare policies. The research will involve collaboration with international health systems to gather and compare data.

Who could benefit from this research

Good fit: Ideal candidates for this research include patients with cardiovascular conditions such as abdominal aortic aneurysms, acute myocardial infarctions, and those requiring advanced cardiovascular procedures.

Not a fit: Patients with non-cardiovascular conditions or those not undergoing advanced cardiovascular procedures may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved cardiovascular treatment strategies and policies that enhance patient outcomes.

How similar studies have performed: Previous research has shown that health technology assessments can significantly impact treatment adoption and patient outcomes, indicating a promising approach for this study.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.