Comparing blood tests for detecting Alzheimer's disease
Head-to-head comparisons of high-performance plasma phospho-tau epitopes for the detection of Alzheimer's disease
This study is looking at how well blood tests can detect Alzheimer's disease by measuring certain proteins in the blood, which could help doctors diagnose the condition more easily and quickly.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pittsburgh at Pittsburgh NIH-funded |
| Lab location | 1 site (Pittsburgh, United States) |
| Project ID | NIH-11077194 on NIH RePORTER |
What this research studies
This research investigates the effectiveness of blood tests that measure specific phosphorylated tau proteins associated with Alzheimer's disease. By analyzing plasma samples for p-tau231, p-tau181, and p-tau217, the study aims to determine how accurately these tests can identify Alzheimer's at various stages. The goal is to simplify the diagnostic process for Alzheimer's, potentially allowing for quicker and more reliable assessments in clinical settings. This could also aid in patient management and recruitment for clinical trials.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals showing early signs of cognitive decline or those at risk for Alzheimer's disease.
Not a fit: Patients with other forms of dementia or cognitive impairment unrelated to Alzheimer's may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate and accessible blood tests for diagnosing Alzheimer's disease.
How similar studies have performed: Other studies have shown promising results with similar blood tests for Alzheimer's detection, indicating a potential for success in this approach.
Where this research is happening
Pittsburgh, United States
- University of Pittsburgh at Pittsburgh — Pittsburgh, United States (Active)
Researchers
- Principal investigator: Pascoal, Tharick — University of Pittsburgh at Pittsburgh
- Study coordinator: Pascoal, Tharick
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.