Community screening for lazy eye using a new retinal scanner

Community-based amblyopia screening using a novel device

['FUNDING_OTHER'] · CHILDREN'S HOSP OF PHILADELPHIA · NIH-11365177

This project compares a common autorefractor and a new retinal scanner to find lazy eye (amblyopia) in young children in clinics and community settings in Nepal.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorCHILDREN'S HOSP OF PHILADELPHIA (nih funded)
Locations1 site (PHILADELPHIA, UNITED STATES)
Trial IDNIH-11365177 on ClinicalTrials.gov

What this research studies

If your child is screened, staff will use either the usual autorefractor or a new retinal birefringence scanner to check for lazy eye. Screenings will occur both in eye clinics and out in community settings so the team can see how the devices perform in real-world locations. The researchers will also compare the costs and how many children are sent for unnecessary follow-up with each approach. The work is linked to a larger community eye health program in Nepal to help make screening practical in low-resource areas.

Who could benefit from this research

Good fit: Ideal candidates are young children—especially preschool-aged children around 3 years up through about 11 years—who live in the communities served in Nepal and can attend clinic or community screening events.

Not a fit: Adults and children who already have a confirmed amblyopia diagnosis and are receiving treatment are unlikely to benefit from this screening-focused project.

Why it matters

Potential benefit: If successful, the new device could find true cases of amblyopia more accurately and reduce unnecessary referrals, making screening cheaper and more effective in low-resource settings.

How similar studies have performed: Standard autorefractors are widely used but often give many false positives, while retinal birefringence scanning is a newer method with promising but still limited evidence outside of controlled research settings.

Where this research is happening

PHILADELPHIA, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.