NIH-funded research NIH-funded research

Community-prescribed opioids and Veterans' safety and pain

Official title: ECCO - Evaluation of Outcomes Associated with Community Care Prescribed Opioids

Funded at Minneapolis VA Medical Center · NIH-11303305 · Data updated 2026-11-12

This project looks at how opioid prescriptions from community providers affect Veterans' safety and pain outcomes since the MISSION Act expanded community care.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionMinneapolis VA Medical Center
NIH-funded
Lab location1 site (Minneapolis, United States)
Project startMarch 1, 2023
Project endFebruary 28, 2027
Funding year2026
NIH project number5I01HX003224-04
Project IDNIH-11303305 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are Veterans who receive care through the VA and also get opioid prescriptions from community (non-VA) providers for acute or chronic pain.

Less likely to help

Non-Veterans and Veterans who receive all care exclusively within VA or who are not prescribed opioids are unlikely to be included or directly benefit.

What this research studies

From your perspective as a Veteran, researchers will compare opioid prescriptions written by community (non-VA) clinicians with those written by VA clinicians using VA medical records, pharmacy fill data, and patient-reported outcome measures. The team will identify higher-risk prescribing patterns (for example, high doses or overlapping prescriptions) and link those patterns to safety events and reported pain outcomes. The work covers the period after the MISSION Act expanded community care and focuses on Veterans who use both VA and non-VA services. Findings are intended to guide better coordination between VA and community providers and improve opioid safety for Veterans.

Why it matters

Potential benefit: If successful, this work could reduce opioid-related harms and improve pain care for Veterans by identifying risky prescribing patterns and informing safer coordination between VA and community clinicians.

How similar studies have gone: Previous VA efforts like the Opioid Safety Initiative reduced high-risk opioid prescribing, but this project is the first to focus on Veteran-centered outcomes after the MISSION Act's expansion of community care.

Where this research is happening

  • Minneapolis VA Medical Center
    Minneapolis, United States
    Active

Researchers

  • Principal investigator: Duan-Porter, Wei — Minneapolis VA Medical Center
  • Study coordinator: Duan-Porter, Wei

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.