NIH-funded research U01 cooperative agreement

Community-delivered buprenorphine for people experiencing homelessness or living in supportive housing

Official title: CE25-149 - Rigorous Evaluation of Community-Delivered Short- and Long-Acting Buprenorphine to People who Experience Homelessness or Live at Permanent Supportive Housing Sites

Funded at Seattle-King County Public Health Dept · NIH-11422048 · Data updated 2026-11-12

A program to deliver buprenorphine, including long-acting injections, directly at encampments, shelters, and supportive housing to reduce overdose risk for people who experience homelessness.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionSeattle-King County Public Health Dept
NIH-funded
Lab location1 site (Seattle, United States)
Project startSeptember 30, 2025
Project endSeptember 29, 2028
Funding year2026
Award (this year)$350,000
NIH project number5U01CE003820-02
Project IDNIH-11422048 on NIH RePORTER

Who could benefit from this research

Could help

Adults who experience homelessness or live in permanent supportive housing and are eligible for buprenorphine treatment.

Less likely to help

People not seeking MOUD or those outside the targeted settings may not experience direct benefit.

What this research studies

If you are homeless or live in supportive housing, this program tests whether getting buprenorphine where you are—at shelters or encampments and through telemedicine—helps prevent overdoses. Nurses will bring medications from a central pharmacy and administer them in the field, using a specific study design to compare outcomes before and after the program. The goal is to see if this community-based approach lowers overdose risk and improves health in a real-world setting. The study uses established methods to evaluate both the impact on individuals and the reach of the program across housing sites.

Why it matters

Potential benefit: If successful, this approach could make MOUD easier to access and reduce overdose deaths for PEH and residents of PSH.

How similar studies have gone: Similar community-based MOUD delivery efforts have shown promise in improving access and outcomes in related populations, with mixed but encouraging results.

Where this research is happening

  • Seattle-King County Public Health Dept
    Seattle, United States
    Active

Researchers

  • Principal investigator: Hood, Julia Elizabeth — Seattle-King County Public Health Dept
  • Study coordinator: Hood, Julia Elizabeth

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.