NIH-funded research R01 grant

Communication Bridge: improving communication for people with primary progressive aphasia

Official title: Communication Bridge: Optimizing an evidence-based intervention for individuals with primary progressive aphasia

Funded at University of Chicago · NIH-11174374 · Data updated 2026-11-12

We are trying a speech and caregiver-focused program delivered by telepractice to help people living with primary progressive aphasia communicate better in everyday life.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Chicago
NIH-funded
Lab location1 site (Chicago, United States)
Project startSeptember 15, 2017
Project endAugust 31, 2028
Funding year2025
Award (this year)$2,211,067
NIH project number5R01AG055425-09
Project IDNIH-11174374 on NIH RePORTER

Who could benefit from this research

Could help

Adults diagnosed with primary progressive aphasia, including cases related to Alzheimer's disease or frontotemporal degeneration, are the primary candidates for this work.

Less likely to help

People without PPA or those with very advanced dementia and minimal ability to participate in communication-focused therapy are unlikely to benefit.

What this research studies

This project refines the Communication Bridge speech-language and psychosocial program for people with primary progressive aphasia and their care partners. The team delivers the intervention remotely via telepractice and uses randomized trial methods to compare outcomes and optimize treatment stages. The program is individualized, focusing on real-world communication, social participation, and strategies for caregivers. The aim is to make benefits durable and ready for broader clinical use.

Why it matters

Potential benefit: If successful, this work could improve everyday communication, social participation, and quality of life for people with PPA and reduce caregiver burden.

How similar studies have gone: Earlier Communication Bridge trials (CB1 and CB2) demonstrated that telepractice delivery is feasible and produced maintained functional communication gains, so this builds on promising prior results.

Where this research is happening

  • University of Chicago
    Chicago, United States
    Active

Researchers

  • Principal investigator: Rogalski, Emily J — University of Chicago
  • Study coordinator: Rogalski, Emily J

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.