Combining therapies to help Veterans with PTSD and suicidal thoughts

A Hybrid Effectiveness-Implementation Trial of Treatments for Veterans with PTSD at Elevated Acute Risk for Suicide

['FUNDING_OTHER'] · VA PUGET SOUND HEALTHCARE SYSTEM · NIH-10907444

This study is looking at a new way to help Veterans with PTSD who are at risk for suicide by testing a combination of two therapies to see if they work better than the usual care, and it aims to find out how well these therapies can be used in Veterans Affairs hospitals.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorVA PUGET SOUND HEALTHCARE SYSTEM (nih funded)
Locations1 site (SEATTLE, UNITED STATES)
Trial IDNIH-10907444 on ClinicalTrials.gov

What this research studies

This research investigates a new treatment approach for Veterans suffering from PTSD who are at high risk for suicide. It aims to compare the effectiveness of a combined therapy that includes Dialectical Behavior Therapy (DBT) and Prolonged Exposure therapy against the current standard care. The study will also explore how well these therapies can be implemented within the Veterans Affairs healthcare system. By focusing on a population that has historically been excluded from treatment trials, this research seeks to provide evidence-based guidance for clinicians.

Who could benefit from this research

Good fit: Ideal candidates for this research are Veterans diagnosed with PTSD who are currently experiencing elevated acute risk for suicide.

Not a fit: Patients who do not have PTSD or are not at risk for suicide may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective treatment options for Veterans with PTSD, significantly reducing their risk of suicide.

How similar studies have performed: Previous research has shown promise in using combined therapy approaches for PTSD, but this specific combination for high-risk individuals is relatively novel.

Where this research is happening

SEATTLE, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.