Combining therapies for liver disease caused by alcohol use
Integrated Therapies for Alcohol use in Alcohol-associated Liver Disease (ITAALD) – Mayo Clinic
This study is looking for better ways to help people with serious liver problems caused by alcohol, by combining the expertise of doctors who treat alcohol use issues and liver disease, and it will test new treatments, including probiotics, to improve health and well-being for those affected.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mayo Clinic Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project ID | NIH-11078499 on NIH RePORTER |
What this research studies
This research investigates new treatment approaches for patients suffering from alcohol-associated liver disease (ALD), particularly focusing on severe alcohol-associated hepatitis and cirrhosis. The study aims to integrate care from both alcohol use disorder and liver disease specialists to improve patient outcomes and reduce stigma associated with alcohol misuse. It will explore the effectiveness of existing medications and novel therapies, including the use of probiotics and other treatments, to enhance survival rates and quality of life for affected individuals. Patients may be monitored for changes in their liver function and drinking behaviors over time.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with severe alcohol-associated hepatitis or decompensated alcohol-associated cirrhosis.
Not a fit: Patients with mild alcohol-associated liver disease or those who do not consume alcohol may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to effective therapies for alcohol-associated liver disease, improving survival rates and quality of life for patients.
How similar studies have performed: Previous studies have shown promising results with integrated treatment approaches for alcohol-related conditions, indicating potential for success in this research.
Where this research is happening
Rochester, United States
- Mayo Clinic Rochester — Rochester, United States (Active)
Researchers
- Principal investigator: Shah, Vijay H. — Mayo Clinic Rochester
- Study coordinator: Shah, Vijay H.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.