Combining therapies for alcohol-related liver disease
Integrated Therapies for Alcohol use in Alcohol-associated Liver Disease (ITAALD)- Cleveland Clinic Clinical Center
This study is looking for better ways to help people with alcohol-related liver problems by combining medical treatments and support for alcohol use, so if you’re dealing with these issues, your progress in both liver health and cutting back on drinking will be closely watched.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cleveland Clinic Lerner Com-Cwru NIH-funded |
| Lab location | 1 site (Cleveland, United States) |
| Project ID | NIH-11078480 on NIH RePORTER |
What this research studies
This research investigates new ways to treat alcohol-associated liver disease (ALD), which is a major cause of liver-related health issues. It aims to integrate care for alcohol use disorder (AUD) and liver disease by combining medical treatments and behavioral therapies. The study will explore the effectiveness of existing medications and novel therapies, as well as the impact of a supportive care team on patient outcomes. Patients will be monitored for improvements in liver function and reduction in alcohol consumption.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with alcohol-associated liver disease, particularly those experiencing severe alcohol-associated hepatitis or decompensated cirrhosis.
Not a fit: Patients who do not have alcohol-associated liver disease or those who are not actively seeking treatment for alcohol use disorder may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to effective treatments for patients suffering from alcohol-associated liver disease, improving their survival rates and quality of life.
How similar studies have performed: Previous studies have shown promising results with integrated treatment approaches for alcohol-related conditions, indicating potential for success in this novel research.
Where this research is happening
Cleveland, United States
- Cleveland Clinic Lerner Com-Cwru — Cleveland, United States (Active)
Researchers
- Principal investigator: Dasarathy, Srinivasan — Cleveland Clinic Lerner Com-Cwru
- Study coordinator: Dasarathy, Srinivasan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.