Combining PET and x-ray imaging to improve breast cancer treatment evaluation
Integrated PET+DBT for optimization of breast cancer therapy
['FUNDING_U01'] · UNIVERSITY OF WASHINGTON · NIH-11136965
This study is testing a new type of scanner that combines two imaging methods to see how well breast cancer treatments are working early on, so doctors can make quick changes if needed, and it's designed for patients undergoing treatment for breast cancer.
Quick facts
| Phase | ['FUNDING_U01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF WASHINGTON (nih funded) |
| Locations | 1 site (SEATTLE, UNITED STATES) |
| Trial ID | NIH-11136965 on ClinicalTrials.gov |
What this research studies
This research investigates a new dual-mode scanner that integrates positron emission tomography (PET) with x-ray tomosynthesis to evaluate breast cancer therapies. By using this innovative imaging technique, the study aims to assess how well breast tumors respond to treatment shortly after it begins, allowing for timely adjustments if necessary. Patients will receive a baseline PET scan followed by a small dose of their planned therapy, with a second scan to monitor the treatment's effectiveness. This approach could help identify the best treatment options for patients before surgery.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with breast cancer who are about to begin neoadjuvant therapy.
Not a fit: Patients with advanced breast cancer who are not candidates for neoadjuvant therapy may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more personalized and effective breast cancer treatments by allowing for early evaluation of therapy responses.
How similar studies have performed: Previous studies have shown that molecular imaging with PET can effectively gauge tumor responses to therapies, indicating a promising approach for this research.
Where this research is happening
SEATTLE, UNITED STATES
- UNIVERSITY OF WASHINGTON — SEATTLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: KINAHAN, PAUL E. — UNIVERSITY OF WASHINGTON
- Study coordinator: KINAHAN, PAUL E.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.