Combining long-acting HIV medicines with long-acting birth control

Co-benefits of co-delivery of long-acting antiretrovirals and contraceptives

NIH-funded research University of Alabama at Birmingham · NIH-11420408

Finding out if giving long-acting injectable HIV treatment and long-acting contraception together helps adolescent girls and young women with HIV stay on treatment and avoid unintended pregnancy.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Alabama at Birmingham NIH-funded
Lab location1 site (Birmingham, United States)
Project IDNIH-11420408 on NIH RePORTER

What this research studies

You would be part of work that looks at how long-acting injectable HIV drugs and long-acting contraceptives work when given together. Researchers will take blood samples to measure drug levels and check for possible interactions, and they will conduct interviews and focus groups to hear about your experiences and preferences. The project mixes lab-based pharmacokinetic tests with qualitative interviews and clinic visits to see how co-delivery could fit into routine care. The team aims to use what they learn to make co-delivery safer, more acceptable, and easier to use in HIV clinics.

Who could benefit from this research

Good fit: Adolescent girls and young women living with HIV (about ages 15–24) who are interested in long-acting injectable ART and long-acting contraceptive options, especially at participating clinics.

Not a fit: People who are not living with HIV, males, older women outside the 15–24 age range, or anyone who cannot or does not want injectable long-acting contraception or ART are unlikely to benefit directly from this project.

Why it matters

Potential benefit: If successful, offering both long-acting HIV treatment and contraception at the same visit could improve treatment adherence, reduce stigma around taking pills, and lower unintended pregnancies.

How similar studies have performed: Long-acting injectable ART and long-acting contraceptives have each been shown to work well on their own, but studying their combined use and any drug interactions in young women is relatively new.

Where this research is happening

Birmingham, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.