Combining hands-on therapy, exercise, and intramuscular electroacupuncture for walking pain from lumbar spinal stenosis

Optimizing Impact of Manual Therapy and Exercise on Lumbar Spinal Stenosis with Neurogenic Claudication: A Multi-Site Feasibility Study

['FUNDING_R01'] · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · NIH-11160739

This project tests whether adding intramuscular electroacupuncture and periodic booster sessions to manual therapy plus exercise can give better and longer-lasting relief for people with lumbar spinal stenosis who have walking-related leg pain (neurogenic claudication).

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF PITTSBURGH AT PITTSBURGH (nih funded)
Locations1 site (PITTSBURGH, UNITED STATES)
Trial IDNIH-11160739 on ClinicalTrials.gov

What this research studies

You would join a two-site feasibility effort run at Boston Medical Center and the University of Pittsburgh that combines hands-on manual therapy and a structured exercise program with or without intramuscular electroacupuncture (IMEA) and later booster visits. Participants will receive scheduled treatment sessions and be followed with regular check-ins to track walking ability, pain, and function over time. The main goal is to see whether this combined approach is practical to deliver and whether it produces stronger and more durable symptom improvements before a larger trial is launched. If successful, the team will use the findings to design a full randomized trial to confirm benefits and guide non-surgical care options.

Who could benefit from this research

Good fit: Ideal candidates are adults—typically older adults—with lumbar spinal stenosis who experience intermittent neurogenic claudication (leg pain or weakness with walking) and who can attend clinic-based manual therapy, exercise, and acupuncture sessions.

Not a fit: People who need urgent surgical decompression for severe or rapidly worsening neurological deficits, who have contraindications to acupuncture or manual therapy (for example uncontrolled bleeding or certain implanted devices), or whose leg symptoms are from non-spinal causes are unlikely to benefit from this program.

Why it matters

Potential benefit: If successful, this approach could give people with lumbar spinal stenosis better, longer-lasting relief of leg pain and walking difficulty and potentially reduce the need for surgery.

How similar studies have performed: Prior trials of manual therapy plus exercise showed modest benefits for neurogenic claudication, and preliminary data on electroacupuncture are promising but high-quality definitive evidence is still lacking.

Where this research is happening

PITTSBURGH, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.