Combining cannabis compounds to treat chronic pain in HIV patients

Beta-caryophyllene (BCP) and cannabidiol (CBD) combination: HIV-1 chronic neuropathic pain

NIH-funded research University of Texas Rio Grande Valley · NIH-10851326

This study is looking at how a mix of two natural compounds, Beta-caryophyllene and cannabidiol, can help relieve chronic nerve pain for people living with HIV, aiming to find a safer and effective alternative to regular pain medications.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of Texas Rio Grande Valley NIH-funded
Lab location1 site (Edinburg, United States)
Project IDNIH-10851326 on NIH RePORTER

What this research studies

This research investigates the use of a combination of Beta-caryophyllene (BCP) and cannabidiol (CBD) to alleviate chronic neuropathic pain associated with HIV-1. The study aims to explore how these cannabis-derived compounds can work together to provide effective pain relief without the common side effects or abuse potential associated with traditional pain medications. By conducting preclinical trials, the researchers will assess the efficacy of this novel therapeutic strategy in managing pain for individuals living with HIV.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals living with HIV who experience chronic neuropathic pain.

Not a fit: Patients who do not have HIV or do not experience neuropathic pain may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide a new, effective treatment option for managing chronic neuropathic pain in HIV patients.

How similar studies have performed: Previous research has shown promise in using cannabis compounds for pain management, suggesting potential success for this combination approach.

Where this research is happening

Edinburg, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.