Combining brain stimulation and therapy to help veterans with chronic pain and depression
Official title: Integrated Repetitive Transcranial Magnetic Stimulation and Acceptance and Commitment Therapy for Veterans with Chronic Pain and Depression
Funded at VA San Diego Healthcare System · NIH-11071939 · Data updated 2026-11-12
This study is exploring a new way to help veterans who are dealing with both chronic pain and depression by using a combination of brain stimulation and therapy to improve their pain and mood.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | VA San Diego Healthcare System NIH-funded |
| Lab location | 1 site (San Diego, United States) |
| Project start | November 1, 2022 |
| Project end | June 30, 2025 |
| Funding year | 2025 |
| NIH project number | 5I21RX004090-03 |
| Project ID | NIH-11071939 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are veterans experiencing chronic pain along with symptoms of depression.
✕Less likely to help
Patients who do not have chronic pain or depression may not benefit from this research.
What this research studies
This research investigates a new treatment approach for veterans suffering from both chronic pain and depression. It combines repetitive Transcranial Magnetic Stimulation (rTMS), a non-invasive brain stimulation technique, with Acceptance and Commitment Therapy (ACT), a psychological intervention. The goal is to improve both pain management and emotional well-being by targeting dysfunctional brain circuits associated with these conditions. Participants will receive rTMS to stimulate specific brain areas while engaging in therapy designed to enhance their coping strategies and overall function.
Why it matters
Potential benefit: If successful, this research could significantly improve the quality of life for veterans by alleviating both chronic pain and depressive symptoms.
How similar studies have gone: Previous research has shown promising results using rTMS for depression and pain management, indicating potential for success with this combined approach.
Where this research is happening
-
VA San Diego Healthcare System
San Diego, United States Active
Researchers
- Principal investigator: Herbert, Matthew — VA San Diego Healthcare System
- Study coordinator: Herbert, Matthew
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.