Combining behavioral therapies to help smokers with HIV quit in Botswana

Testing the Combination of Behavioral Activation and Problem Solving as a Novel Behavioral Smoking Cessation Intervention for Smokers with HIV in Botswana

['FUNDING_R01'] · UNIVERSITY OF PENNSYLVANIA · NIH-10978303

This study is testing a new way to help people with HIV in Botswana quit smoking by using two supportive methods that encourage healthy activities and tackle feelings of depression, making it easier for them to stop smoking for good.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF PENNSYLVANIA (nih funded)
Locations1 site (PHILADELPHIA, UNITED STATES)
Trial IDNIH-10978303 on ClinicalTrials.gov

What this research studies

This research investigates a new approach to help individuals with HIV in Botswana quit smoking by combining two behavioral therapies: behavioral activation and problem-solving. The study recognizes the unique challenges faced by HIV-positive smokers, such as high rates of depression and limited access to pharmacotherapy. By focusing on increasing engagement in healthy activities and addressing depressive symptoms, the research aims to create a feasible smoking cessation intervention tailored for this population. Participants will receive support to develop problem-solving skills alongside behavioral activation techniques to improve their chances of quitting smoking.

Who could benefit from this research

Good fit: Ideal candidates for this research are HIV-positive individuals in Botswana who smoke and may also experience depressive symptoms.

Not a fit: Patients who do not smoke or are not HIV-positive may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly improve smoking cessation rates among HIV-positive individuals in Botswana, leading to better health outcomes.

How similar studies have performed: Previous research has shown promise in using behavioral activation for smoking cessation, particularly in populations with comorbid conditions, suggesting this approach may be effective.

Where this research is happening

PHILADELPHIA, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.