Combining behavior therapy with buprenorphine to treat opioid use disorder

The Role of Behavior Therapy Combined with Buprenorphine for the Treatment of Opioid Use Disorder

NIH-funded research Mclean Hospital · NIH-10817128

This study is looking at whether adding behavior therapy to buprenorphine can help people with opioid use disorder feel better and recover more effectively, and it aims to find out which patients might benefit the most from this combined approach.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionMclean Hospital NIH-funded
Lab location1 site (Belmont, United States)
Project IDNIH-10817128 on NIH RePORTER

What this research studies

This research investigates how combining behavior therapy with buprenorphine can improve treatment outcomes for individuals with opioid use disorder. The study aims to identify which specific groups of patients may benefit most from the addition of behavior therapy, as current treatments do not work effectively for everyone. By analyzing data from multiple clinical trials, the research seeks to enhance personalized treatment approaches for opioid use disorder. Patients participating in this research may receive tailored interventions based on their unique responses to treatment.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with opioid use disorder who are currently receiving or are eligible for buprenorphine treatment.

Not a fit: Patients who are not diagnosed with opioid use disorder or those who are not seeking treatment for opioid addiction may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective and personalized treatment options for individuals struggling with opioid use disorder.

How similar studies have performed: Previous research has shown mixed results regarding the effectiveness of combining behavior therapy with medication for substance use disorders, indicating that this approach is still being explored.

Where this research is happening

Belmont, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.