Combined-Therapy Protocols for Anxiety and Fear-Related Disorders
Official title: Combined-Therapy Protocols for Cognitive/Behavioral Disorders
Funded at Albany Research Institute, INC. · NIH-11422904 · Data updated 2026-11-12
Aims to develop fast-acting brain-based therapies to help people with anxiety and related disorders by using targeted brain stimulation and behavioral approaches.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Albany Research Institute, INC. NIH-funded |
| Lab location | 1 site (Albany, United States) |
| Project start | September 10, 2014 |
| Project end | May 31, 2031 |
| Funding year | 2026 |
| Award (this year) | $367,355 |
| NIH project number | 2P41EB018783-11A1 |
| Project ID | NIH-11422904 on NIH RePORTER |
Who could benefit from this research
✓Could help
Individuals with anxiety disorders or PTSD-like symptoms who might benefit from advanced neuromodulation and behavioral therapies.
✕Less likely to help
People without anxiety-related conditions or those who are not candidates for neuromodulation therapies may not benefit.
What this research studies
This project builds on studies with people who already had brain monitoring electrodes before epilepsy surgery to understand circuits in the amygdala and limbic system that control fear and emotion. It plans to pair deep brain stimulation with behavioral therapies to produce quicker relief from fear and anxiety, guided by biomarkers. The work will identify neurometric and psychometric signals that predict therapy benefits and use them to optimize treatment delivery. The overarching goal is to translate these findings into faster, effective options for patients with anxiety disorders and PTSD-like symptoms.
Why it matters
Potential benefit: If successful, patients could experience faster reduction in fear and anxiety through refined brain- and behavior-based therapies.
How similar studies have gone: Previous work identified biomarkers and demonstrated potential for rapid therapeutic effects with neuromodulation in similar contexts.
Where this research is happening
-
Albany Research Institute, INC.
Albany, United States Active
Researchers
- Principal investigator: Brunner, Peter — Albany Research Institute, INC.
- Study coordinator: Brunner, Peter
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.