Colorectal cancer genomic profiling across diverse patient groups
Genome Characterization Unit
['FUNDING_OTHER'] · UNIVERSITY OF SOUTHERN CALIFORNIA · NIH-11192766
This project will use comprehensive tumor genome and molecular testing to find differences in colorectal cancers across diverse patient groups to support more personalized care.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF SOUTHERN CALIFORNIA (nih funded) |
| Locations | 1 site (Los Angeles, UNITED STATES) |
| Trial ID | NIH-11192766 on ClinicalTrials.gov |
What this research studies
We will work with people with colorectal cancer to collect tumor samples and clinical information and perform DNA, RNA, and methylation sequencing. Bioinformatics will combine those results with clinical data and input from patient engagement teams to look for molecular differences across populations, including Hispanic patients. The team will compare genomic features that might affect treatment choices or trial eligibility. Findings will help guide more representative research and future tailored care.
Who could benefit from this research
Good fit: People with colorectal cancer who can provide tumor tissue and clinical information, including those from diverse backgrounds, are the ideal candidates for participation.
Not a fit: People without colorectal cancer or those unable or unwilling to provide tumor samples and clinical data are unlikely to receive direct benefit from this project.
Why it matters
Potential benefit: If successful, this could help match patients to treatments and clinical trials that fit the molecular features of their tumors, especially for underrepresented groups.
How similar studies have performed: Genomic profiling has already guided treatment for some cancers, but comprehensive sequencing across diverse colorectal cancer populations is still an emerging approach.
Where this research is happening
Los Angeles, UNITED STATES
- UNIVERSITY OF SOUTHERN CALIFORNIA — Los Angeles, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SALHIA, BODOUR — UNIVERSITY OF SOUTHERN CALIFORNIA
- Study coordinator: SALHIA, BODOUR
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.