Collecting and processing human tissue to improve pain treatment

Human Tissue Procurement and Processing Core

['FUNDING_OTHER'] · BRIGHAM AND WOMEN'S HOSPITAL · NIH-10928100

This study is looking at human tissue samples from people with chronic pain to learn more about how pain works, with the hope of finding better treatments for those who suffer from it.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorBRIGHAM AND WOMEN'S HOSPITAL (nih funded)
Locations1 site (BOSTON, UNITED STATES)
Trial IDNIH-10928100 on ClinicalTrials.gov

What this research studies

This research focuses on obtaining high-quality human tissue samples from post-mortem donors and chronic pain patients to better understand pain mechanisms. By utilizing advanced techniques like single-cell genomics, the project aims to identify new therapeutic targets for chronic pain, particularly in areas like the dorsal root ganglia. The Human Tissue Procurement and Processing Core will ensure that these samples are collected ethically and processed for detailed analysis, which could lead to more effective pain treatments. The research is already in progress, having successfully collected and processed samples from multiple donors.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals with chronic pain conditions who are willing to provide tissue samples post-mortem.

Not a fit: Patients who do not have chronic pain or are not willing to participate in tissue donation may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to the development of novel and effective treatments for patients suffering from chronic pain.

How similar studies have performed: Other research has shown promise in using human tissue samples for understanding pain mechanisms, indicating that this approach could yield significant insights.

Where this research is happening

BOSTON, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.