Collecting and monitoring patient samples for immune system recovery after stem cell transplants
Biobanking and Immunologic Monitoring
This study is all about helping patients who have had a stem cell transplant by collecting and storing their blood and bone marrow samples, so researchers can learn how the immune system heals and find better ways to prevent or treat complications like chronic graft-versus-host disease.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Dana-Farber Cancer Inst NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10914135 on NIH RePORTER |
What this research studies
This research focuses on creating a centralized laboratory resource to collect, preserve, and distribute patient samples, such as blood and bone marrow, to study how the immune system recovers after allogeneic hematopoietic stem cell transplantation (HCT). Patients enrolled in clinical trials will have their samples monitored over time to understand the effects of various immune interventions aimed at preventing or treating chronic graft-versus-host disease (GVHD). The samples collected will be processed and stored for future analysis, providing valuable data for ongoing and future research efforts.
Who could benefit from this research
Good fit: Ideal candidates for this research include patients aged 21 and older who are undergoing allogeneic hematopoietic stem cell transplantation.
Not a fit: Patients who are not undergoing stem cell transplantation or who are younger than 21 years old may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for managing immune recovery and reducing complications like chronic GVHD in patients undergoing stem cell transplants.
How similar studies have performed: Previous research has shown success in using similar biobanking and monitoring approaches to improve patient outcomes in stem cell transplantation.
Where this research is happening
Boston, United States
- Dana-Farber Cancer Inst — Boston, United States (Active)
Researchers
- Principal investigator: Ritz, Jerome — Dana-Farber Cancer Inst
- Study coordinator: Ritz, Jerome
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.