Collecting and analyzing glioblastoma patient biopsies
Official title: MOSAIC: Biospecimen Core
Funded at Mayo Clinic Arizona · NIH-10930917 · Data updated 2026-11-12
This study is looking at tissue samples from patients with glioblastoma to learn how the tumors change with treatment, helping doctors understand how to better fight this type of brain cancer.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mayo Clinic Arizona NIH-funded |
| Lab location | 1 site (Scottsdale, United States) |
| Project start | September 18, 2023 |
| Project end | August 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $281,597 |
| NIH project number | 5U54CA274504-02 |
| Project ID | NIH-10930917 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients diagnosed with glioblastoma who are undergoing treatment and can provide biopsy samples.
✕Less likely to help
Patients with other types of brain tumors or those who are not undergoing treatment for glioblastoma may not benefit from this research.
What this research studies
This research focuses on obtaining, processing, imaging, and analyzing biopsies from patients with glioblastoma, a type of brain cancer. The goal is to understand how these tumors respond to treatment by examining the tissue states before and after therapy. The research involves advanced techniques such as RNA sequencing and immunohistochemistry to analyze the biopsies, which will help build a framework for understanding tumor behavior and treatment responses. Patients' biopsies will be crucial for both clinical and experimental studies conducted at Mayo Clinic Arizona and Columbia University Medical Center.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies for glioblastoma patients by providing insights into tumor biology and therapy responses.
How similar studies have gone: Previous research has shown success in using similar biopsy analysis techniques to understand tumor biology and treatment responses in various cancers.
Where this research is happening
-
Mayo Clinic Arizona
Scottsdale, United States Active
Researchers
- Principal investigator: Canoll, Peter — Mayo Clinic Arizona
- Study coordinator: Canoll, Peter
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.