Collecting and analyzing clinical data from lung transplant patients
Official title: Core B: Human and Clinical Phenotyping Core
Funded at Northwestern University at Chicago · NIH-10933921 · Data updated 2026-11-12
This study is looking at information from lung transplant patients to better understand complications they might face, like primary graft dysfunction and chronic lung allograft dysfunction, using advanced techniques to find new ways to help improve their health.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Northwestern University at Chicago NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project start | September 17, 2024 |
| Project end | July 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $503,232 |
| NIH project number | 1P01HL169188-01A1 |
| Project ID | NIH-10933921 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who are undergoing or have recently undergone lung transplantation.
✕Less likely to help
Patients who have not received a lung transplant or those with other unrelated chronic conditions may not benefit from this research.
What this research studies
This research focuses on gathering and analyzing clinical data from patients who have undergone lung transplantation. It aims to create a comprehensive multi-omics dataset that includes genomic and proteomic information, which will help in understanding complications such as primary graft dysfunction (PGD) and chronic lung allograft dysfunction (CLAD). The project will utilize advanced techniques like flow cytometry and single-cell RNA sequencing to study biological materials collected from these patients. By applying machine learning methods, the research seeks to identify biomarkers and therapeutic targets that could improve patient outcomes.
Why it matters
Potential benefit: If successful, this research could lead to better diagnostic tools and treatments for lung transplant recipients, potentially improving their long-term health and survival rates.
How similar studies have gone: Other research has shown success in using multi-omics approaches to improve understanding of transplant-related complications, indicating that this methodology is promising.
Where this research is happening
-
Northwestern University at Chicago
Chicago, United States Active
Researchers
- Principal investigator: Singer, Benjamin David — Northwestern University at Chicago
- Study coordinator: Singer, Benjamin David
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.