Collagen-based tissue guide to treat stress urinary incontinence in women
Official title: Collagen-based tissue guidance biofabric for treatment of stress urinary incontinence in women
Funded at Collamedix INC. · NIH-11367360 · Data updated 2026-11-12
A new collagen-based implant approach is being developed to help women with stress urinary incontinence experience better results and fewer complications from current mesh slings.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Collamedix INC. NIH-funded |
| Lab location | 1 site (Cleveland, United States) |
| Project start | April 15, 2020 |
| Project end | May 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $933,974 |
| NIH project number | 5R44HD102241-05 |
| Project ID | NIH-11367360 on NIH RePORTER |
Who could benefit from this research
✓Could help
Women with stress urinary incontinence who are candidates for implant-based therapies and are seeking alternatives to current mesh slings.
✕Less likely to help
Women not eligible for implant-based therapy or with conditions that preclude collagen implants may not benefit.
What this research studies
This project uses a collagen-based tissue guide made with a patented electrochemical process to create dense, ligament-like threads that support pelvic tissues. The implant is designed to be resorbed and remodeled as strong tissue grows through it, potentially reducing chronic pain and device-related complications. The team at CollaMedix aims to translate this material into a safe, implantable option for women suffering from SUI who are hesitant about current mesh devices.
Why it matters
Potential benefit: If successful, patients may have a safer, more natural-supporting treatment for stress urinary incontinence with fewer side effects.
How similar studies have gone: Prior collagen-based implants have shown promise in tissue integration, but this exact approach is being investigated for SUI.
Where this research is happening
-
Collamedix INC.
Cleveland, United States Active
Researchers
- Principal investigator: Shankar, Subba — Collamedix INC.
- Study coordinator: Shankar, Subba
Related research
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A new collagen-based implant for women with stress urinary incontinence
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.