Collaborative care program to boost PrEP uptake and HIV care for young men

The Collaborative Care PrTNER (Prevention, Treatment, Navigation, Engagement, Resource) Project

NIH-funded research Children's Hosp of Philadelphia · NIH-11390929

A team-based care program offers young men (15–29) who use substances help to start PrEP if at risk or improve HIV treatment to lower viral load.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionChildren's Hosp of Philadelphia NIH-funded
Lab location1 site (Philadelphia, United States)
Project IDNIH-11390929 on NIH RePORTER

What this research studies

You would be enrolled in a randomized trial comparing a coordinated care program to usual care, with follow-up over about 12 months. The program integrates substance-use treatment into HIV and PrEP primary care and adds support from a peer coach plus psychiatric feedback for clinicians. The team helps with prevention (PrEP) for those at risk and treatment navigation for those living with HIV, aiming to increase PrEP starts and reduce viral load through better engagement in substance-use services. Visits will include clinic-based care, counseling, and coordinated follow-up to track outcomes.

Who could benefit from this research

Good fit: Young men aged about 15–29 who use alcohol or other substances and are either at risk for HIV (PrEP candidates) or living with HIV are the ideal participants.

Not a fit: People outside the young male age range, those without substance-use concerns, or those neither at risk for HIV nor living with HIV are unlikely to be eligible or directly benefit.

Why it matters

Potential benefit: If successful, this program could help more young men start PrEP and achieve lower HIV viral loads by integrating substance-use treatment into HIV care.

How similar studies have performed: Other integrated HIV and substance-use care programs have shown promising results for improving treatment engagement and PrEP uptake, but this specific collaborative model for young men is relatively new and is being rigorously tested.

Where this research is happening

Philadelphia, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.