Coach Mpilo peer support for men with TB and HIV in Eastern Cape, South Africa

Assessing the Feasibility of Coach Mpilo for Men with TB and HIV in Eastern Cape, South Africa

['FUNDING_OTHER'] · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · NIH-11175983

This project tests whether a peer-support program called Coach Mpilo helps men in Eastern Cape, South Africa stay on TB treatment and manage HIV.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorARIZONA STATE UNIVERSITY-TEMPE CAMPUS (nih funded)
Locations1 site (SCOTTSDALE, UNITED STATES)
Trial IDNIH-11175983 on ClinicalTrials.gov

What this research studies

If you join, you would help the team adapt Coach Mpilo so it fits men who are starting TB treatment, including men living with HIV. The researchers will use interviews, coach simulations, and a small pre-test to tailor the program before a randomized trial. In the trial, about 120 men starting TB treatment will be randomly assigned to receive Coach Mpilo or usual clinic-based support and followed for retention and TB treatment outcomes. The main goal is to see if the program is usable and acceptable to men and to collect early data on treatment completion and HIV viral suppression.

Who could benefit from this research

Good fit: Adult men (roughly 21 years and older) in the Eastern Cape, South Africa who are initiating TB treatment, including those with HIV, are the intended participants.

Not a fit: Women, children, people not starting TB treatment, or those living outside the study area are not likely to benefit from participating in this project.

Why it matters

Potential benefit: If successful, the program could help men complete TB treatment and improve HIV viral control through peer support.

How similar studies have performed: Peer-support programs like Coach Mpilo have shown promise for supporting HIV treatment in South Africa, but applying and testing this approach specifically for men starting TB treatment (with HIV co-infection) is a newer use being tested here.

Where this research is happening

SCOTTSDALE, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome Virus

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.