Closing the GAPS: Guideline Adherence, Prevention and Surveillance in Hereditary Cancer
Funded at Nest Genomics · NIH-11415655 · Data updated 2026-11-12
Aims to build a genomic-integration system in EMRs to better identify, educate, and guide patients with inherited cancer risk.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Nest Genomics NIH-funded |
| Lab location | 1 site (Albany, United States) |
| Project start | September 19, 2024 |
| Project end | August 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $790,626 |
| NIH project number | 5R42HG013908-03 |
| Project ID | NIH-11415655 on NIH RePORTER |
Who could benefit from this research
✓Could help
Individuals with or at risk for inherited cancer syndromes, including adolescents and young adults, who are undergoing genomic testing or surveillance.
✕Less likely to help
Patients unlikely to benefit include those without hereditary cancer risk or those not engaged in genomic testing or longitudinal surveillance.
What this research studies
This project seeks to create a comprehensive, longitudinal genomic infrastructure that works with electronic medical records to help clinicians order tests, deliver results, and provide ongoing decision support for patients with inherited cancer risk. It focuses on empowering patients—especially adolescents and young adults—by giving them knowledge and tools to participate in their care. The effort will pilot genomic data integration, informed consent processes, and CDS features in real-world clinical settings. By improving adherence to guidelines and streamlining prevention and surveillance, it aims to improve long-term outcomes for individuals with hereditary cancer risk.
Why it matters
Potential benefit: If successful, patients could receive more timely and accurate risk assessment, better preventive care, and clearer education and involvement in their own health decisions.
How similar studies have gone: Prior work shows that integrating genomics into EMRs can improve test ordering and result delivery, but long-term, scalable infrastructure is still evolving.
Where this research is happening
-
Nest Genomics
Albany, United States Active
Researchers
- Principal investigator: Snir, Moran — Nest Genomics
- Study coordinator: Snir, Moran
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.