Clinical resource for Alzheimer's participant evaluations and sample collection
Core B - Clinical Core
This program gathers brain scans, memory testing, blood and spinal fluid samples from middle-aged and older adults to support Alzheimer's research.
Quick facts
| Grant type | P30 center grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Wisconsin-Madison NIH-funded |
| Lab location | 1 site (Madison, United States) |
| Project ID | NIH-11381767 on NIH RePORTER |
What this research studies
If you join, you would have standardized memory and neurobehavioral testing, brain imaging (MRI and PET), and provide blood and occasionally cerebrospinal fluid and DNA samples, with an option to consent to brain donation. Your medical records can be linked to the research data to give a fuller picture of health over time. The Core enrolls people with mild cognitive impairment, mild dementia, and cognitively unimpaired middle-aged and older adults (45+ and 65+ groups). The team also helps find and refer people to other Alzheimer’s studies and supports standardized testing and sample coordination for researchers.
Who could benefit from this research
Good fit: Ideal candidates are adults 45 years and older — including cognitively unimpaired people, those with mild cognitive impairment, or mild dementia — who can travel to Madison and are willing to have imaging and provide blood and possibly CSF samples.
Not a fit: People seeking immediate personal treatment or those unwilling to undergo imaging, lumbar puncture, or data sharing are unlikely to receive direct clinical benefit from participation.
Why it matters
Potential benefit: This could help researchers find earlier biological signs of Alzheimer’s and speed the development of better tests and future treatments.
How similar studies have performed: Programs like the Alzheimer's Disease Neuroimaging Initiative (ADNI) have used the same kinds of scans and biomarkers and have successfully advanced understanding of early Alzheimer’s changes, so this approach builds on established methods.
Where this research is happening
Madison, United States
- University of Wisconsin-Madison — Madison, United States (Active)
Researchers
- Principal investigator: Carlsson, Cynthia M — University of Wisconsin-Madison
- Study coordinator: Carlsson, Cynthia M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.