Clinical Resource for Alzheimer’s in Older Asian Adults
Core C: Clinical Core
This project collects culturally and linguistically adapted clinical and cognitive information from older Asian adults to improve Alzheimer’s diagnosis and understanding of risk.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-11160745 on NIH RePORTER |
What this research studies
If you join, clinicians will use harmonized exams and questionnaires that are adapted for different Asian languages and cultures to record your medical and lifestyle history, neurological findings, and cognitive test results. The team combines data across sites to reach consensus diagnoses for people with Alzheimer’s dementia, mild cognitive impairment, or normal cognition. They will keep revising and validating the data collection packets so tests work fairly across diverse Asian subgroups. The Core also provides clinical expertise to guide related research projects focused on Alzheimer’s in Asian American and Asian Canadian populations.
Who could benefit from this research
Good fit: Older adults of Asian descent, including those with Alzheimer’s dementia, mild cognitive impairment, or normal cognition, who are willing to share medical and lifestyle history and undergo cognitive and neurological evaluations.
Not a fit: Younger individuals, people not of Asian descent, or those seeking immediate clinical treatment rather than diagnostic-focused research are unlikely to receive direct benefit from participation.
Why it matters
Potential benefit: Could lead to more accurate, culturally appropriate diagnosis and screening tools for Alzheimer’s in Asian American and Asian Canadian older adults.
How similar studies have performed: While some studies have adapted cognitive tests for specific Asian groups, this is one of the first coordinated, multi-site efforts to harmonize and validate culturally fair assessments for Asian American and Asian Canadian populations.
Where this research is happening
Philadelphia, United States
- University of Pennsylvania — Philadelphia, United States (Active)
Researchers
- Principal investigator: Henderson, Victor — University of Pennsylvania
- Study coordinator: Henderson, Victor
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.