NIH-funded research NIH-funded research

Clinical project focusing on how diabetes and related factors influence Alzheimer’s risk

Official title: Clinical Project

Funded at North Carolina Agri & Tech St Univ · NIH-11234890 · Data updated 2026-11-12

A nationwide effort at studying how type 2 diabetes and other health factors contribute to Alzheimer's risk and disparities, with potential to guide prevention.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionNorth Carolina Agri & Tech St Univ
NIH-funded
Lab location1 site (Greensboro, United States)
Project startAugust 4, 2026
Project endFebruary 28, 2031
Funding year2026
Award (this year)$425,708
NIH project number1U54MD020891-01
Project IDNIH-11234890 on NIH RePORTER

Who could benefit from this research

Could help

Adults with type 2 diabetes, obesity, insulin resistance, or other cardiometabolic risk factors, and populations experiencing health disparities related to these conditions.

Less likely to help

Individuals without risk factors or interest in metabolic-dementia links may see limited direct benefit.

What this research studies

This project explores how cardiometabolic factors like obesity, insulin resistance, and type 2 diabetes intersect with Alzheimer’s risk, aiming to uncover mechanisms and interventions. It emphasizes disparities, noting higher risk among Black Americans and the potential to reduce those gaps. The research will be conducted at North Carolina A&T State University with a focus on translating findings into prevention and treatment strategies for adults at risk. The grant supports long-term, collaborative work to understand how metabolic health shapes dementia risk in diverse populations.

Why it matters

Potential benefit: If successful, findings could inform personalized prevention and treatment strategies to reduce dementia risk in people with diabetes and metabolic syndrome.

How similar studies have gone: Prior research has linked diabetes and insulin resistance to increased dementia risk, with ongoing work exploring mechanisms and interventions.

Where this research is happening

  • North Carolina Agri & Tech St Univ
    Greensboro, United States
    Active

Researchers

  • Principal investigator: Russell, Ryan Damion — North Carolina Agri & Tech St Univ
  • Study coordinator: Russell, Ryan Damion

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.