Clinical Metabolism Support Center
Clinical Metabolism Core
['FUNDING_P30'] · YALE UNIVERSITY · NIH-11364111
This center measures how people with diabetes process sugars, fats, and proteins using safe labeled atoms.
Quick facts
| Phase | ['FUNDING_P30'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | YALE UNIVERSITY (nih funded) |
| Locations | 1 site (NEW HAVEN, UNITED STATES) |
| Trial ID | NIH-11364111 on ClinicalTrials.gov |
What this research studies
This center at Yale helps doctors measure how people's bodies process nutrients by using safe non-radioactive labeled atoms called stable isotopes. They analyze blood, urine, tissue, and biopsy samples using high-tech machines like mass spectrometers and NMR to track how sugars, fats, and amino acids move through the body. The core provides trained staff and equipment to extract, prepare, and run the detailed tests researchers need and to interpret the results. They also offer services to researchers working with animal and cell models, but the main focus is supporting patient-oriented metabolic studies related to diabetes.
Who could benefit from this research
Good fit: Adults with adult-onset (type 2) diabetes or other metabolic conditions who are enrolled in clinical studies at Yale or collaborating sites are the main candidates for these services.
Not a fit: People without metabolic conditions or those unable to travel to or send samples to Yale are unlikely to benefit directly from this core.
Why it matters
Potential benefit: If successful, this service could help pinpoint metabolic problems and guide more personalized treatments for people with diabetes.
How similar studies have performed: Using stable isotopes with mass spectrometry and NMR is a well-established approach that has previously revealed important changes in glucose and fat metabolism in diabetes.
Where this research is happening
NEW HAVEN, UNITED STATES
- YALE UNIVERSITY — NEW HAVEN, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SHULMAN, GERALD I — YALE UNIVERSITY
- Study coordinator: SHULMAN, GERALD I
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Adult-Onset Diabetes Mellitus