Clinical and Data Support for Pediatric Dengue
CORE C: Clinical, Data Management and Statistical Modeling Core
This core runs long-term clinical follow-up and collects medical information and blood samples from children with dengue in Nicaragua and the Philippines to support dengue research.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Berkeley NIH-funded |
| Lab location | 1 site (Berkeley, United States) |
| Project ID | NIH-11111754 on NIH RePORTER |
What this research studies
You would be followed in a pediatric dengue cohort where staff enroll children, provide medical care, and collect and store blood samples and clinical information. The core maintains and updates secure databases that combine clinical records and sample inventories from cohorts in Managua, Nicaragua, the Philippines, and an NIH vaccine challenge study. It performs quality control, prepares tailored datasets, and helps select and distribute specimens to the research projects that need them. The core team coordinates consent, human-subjects documentation, and ensures sample and data sharing for approved research.
Who could benefit from this research
Good fit: Ideal candidates are children (roughly 0–11 years old) in the participating cohorts—for example, families in Managua, Nicaragua, or enrolled Philippine cohorts—whose caregivers agree to regular clinic visits and blood sampling.
Not a fit: Adults, people without dengue exposure, and children whose caregivers decline follow-up visits or blood draws are unlikely to gain direct benefits from participating.
Why it matters
Potential benefit: If successful, the core could accelerate discoveries about how dengue affects children and help guide better vaccines and treatments by making high-quality data and samples available to researchers.
How similar studies have performed: Long-running pediatric dengue cohorts have previously produced important findings about immunity and disease risk, so this core extends well-established and successful cohort methods.
Where this research is happening
Berkeley, United States
- University of California Berkeley — Berkeley, United States (Active)
Researchers
- Principal investigator: Gordon, Aubree L — University of California Berkeley
- Study coordinator: Gordon, Aubree L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.