Cleaner indoor air for Ugandan homes

Optimizing air purification strategies to reduce household PM2.5 exposure in Uganda

NIH-funded research Massachusetts General Hospital · NIH-11135418

Trying portable HEPA air cleaners and reliable power options to lower fine particle (PM2.5) exposure for families and children living in Ugandan households.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionMassachusetts General Hospital NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-11135418 on NIH RePORTER

What this research studies

You would join about 20 households in an established Ugandan cohort where researchers place portable HEPA air cleaners in homes and monitor indoor air quality. The team will run controlled experiments in simulation spaces and real households to find the best placement and filtration settings to cut particulate levels. They'll design and test power solutions (like batteries) so the cleaners can run when electricity is unreliable. Families, especially those with a child who has had pneumonia, will be asked about ease of use and how often the devices are kept on while researchers measure PM2.5 and adherence.

Who could benefit from this research

Good fit: Ideal candidates are Ugandan households (urban or rural) with children, particularly families with a history of childhood pneumonia, willing to host and use a portable air cleaner while being monitored.

Not a fit: People living outside the selected Ugandan communities or households without significant indoor particulate sources or interest in hosting/using a cleaner may not receive direct benefit from this project.

Why it matters

Potential benefit: If successful, the project could lower indoor fine particle exposure in homes and help reduce respiratory risks for children and adults.

How similar studies have performed: HEPA-based portable air cleaners have lowered indoor PM2.5 in prior studies, but evidence is limited for low-resource settings with unreliable electricity and for families of children with pneumonia.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.