City of Hope's Program for Blood and Marrow Transplants
BMT CTN Core - City of Hope National Medical Center
This grant helps City of Hope continue its important work in developing better blood and marrow transplant treatments for patients with blood cancers and other serious conditions.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Beckman Research Institute/city of Hope NIH-funded |
| Lab location | 1 site (Duarte, United States) |
| Project ID | NIH-11170570 on NIH RePORTER |
What this research studies
City of Hope aims to continue its long-standing commitment to improving blood and marrow transplants for patients. For over 50 years, our program has been at the forefront of creating new clinical trials to enhance transplant outcomes for those with blood cancers and other non-cancerous disorders. We focus on finding ways to reduce common problems like relapse, graft-versus-host disease, and infections after transplant. This work includes developing a new platform trial for patients with a specific type of leukemia or MDS that is currently very hard to treat.
Who could benefit from this research
Good fit: Ideal candidates for future trials supported by this grant might include adults aged 21 and older who have hematologic malignancies or non-malignant disorders, particularly those with TP53-mutated AML or MDS.
Not a fit: Patients who are not candidates for blood and marrow transplantation or who do not have the specific conditions being studied may not directly benefit from this particular research.
Why it matters
Potential benefit: If successful, this work could lead to more effective and safer blood and marrow transplant options, especially for patients with challenging conditions like TP53-mutated AML or MDS.
How similar studies have performed: City of Hope has a 50-year history of developing successful clinical trials in blood and marrow transplantation, and has contributed to the Blood and Marrow Transplant Clinical Trials Network for 20 years.
Where this research is happening
Duarte, United States
- Beckman Research Institute/city of Hope — Duarte, United States (Active)
Researchers
- Principal investigator: Nakamura, Ryotaro — Beckman Research Institute/city of Hope
- Study coordinator: Nakamura, Ryotaro
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.